Generalized papular and sclerodermoid eruption: Scleromyxedema

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Scleromyxedema with Subcutaneous Nodules: Successful Treatment with Thalidomide and Intravenous Immunoglobulin

Scleromyxedema is a rare cutaneous mucinosis, usually presenting with generalized papular eruption and sclerodermoid induration, monoclonal gammopathy and systemic manifestations. An atypical clinical presentation with cutaneous and subcutaneous nodules has been reported rarely. In recent years, intravenous immunoglobulin (IVIg) appears to be the therapy of choice for scleromyxedema. Treatment ...

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Scleromyxedema without Paraproteinemia: Treatment with Thalidomide and Prednisolone

Scleromyxedema is a rare and distinctive variant of cutaneous mucinoses of unknown etiology. It is presenting with generalized papular eruption and sclerodermoid induration. Numerous treatment modalities have been reported to produce partial or permanent responses. This study reports on a case of scleromyxedema without paraproteinemia in a subject who experienced a partial response to thalidomi...

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Paraneoplastic atypical scleromyxedema with advanced gastric cancer

INTRODUCTION Scleromyxedema is a rare, chronic and progressive disorder of unknown origin characterized by a generalized papular eruption and sclerodermoid induration, with histopathologic features of mucin deposition and fibroblast proliferation. The disease is usually associated with a monoclonal gammopathy. However, only a few cases associated with neoplasms have been reported. We report a c...

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Acral papular eruption.

On examination, there were multiple skin colored to erythematous and edematous papules of about 1 to 5 mm size [Figure 1]. Many of the lesions, located over the extensor aspects of hands [Figure 2], forearms, elbows and upper arms were topped with tiny crusts and scales whereas others showed a central dusky hue. Examination of the conjunctiva revealed mild icterus. Bilateral axillary, epitrochl...

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Palifermin-associated papular eruption.

BACKGROUND Palifermin is a recombinant human keratinocyte growth factor that is used to reduce the duration and severity of oral mucositis in patients undergoing hematopoietic stem cell transplantation after myelotoxic therapy. Cutaneous adverse reactions associated with keratinocyte growth factor are reported to be rash, pruritus, and erythema. OBSERVATIONS After receiving palifermin followi...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology

سال: 2010

ISSN: 0378-6323

DOI: 10.4103/0378-6323.69096